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Sponsors developing antivirals should note the agency's acceptance of household-contact trial designs and symptomatic risk reduction as primary endpoints

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So far there is only one high-resolution prefusion structure of gB, namely from the beta-herpesvirus human cytomegalovirus (HCMV), that was captured in this state using a specific inhibitor and chemical crosslinking and purified using an antigen-binding fragment (Fab) of a neutralizing antibody 4

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